Series with the first letter - "S"
- Spaced (1999–2001)
- Spartacus (2010–2013)
- Spartacus: Gods of the Arena (2011)
- Special (2019–…)
- Speechless (2016–…)
- Speed Is the New Black (2017–…)
- Speed Racer (1967–1968)
- Speed Racer: The Next Generation (2008–2013)
- Speed with Guy Martin (2013–…)
- Spencer Sisters (2023–…)
- Spider-Man (1994–1998)
- Spider-Man (2017–…)
- Spider-Man (1967–1970)
- Spider-Man Unlimited (1999–2005)
- Spidey and His Amazing Friends (2021–…)
- Spies of Warsaw (2013–…)
- Spin (2012–2016)
- Spin City (1996–2002)
- Spinning Out (2020)
- Spiral (2005–…)
- Spirit Rangers (2022–…)
- Spirit Riding Free (2017–…)
- Spirit Riding Free: Pony Tales (2017–…)
- Spitting Image (2020–…)
- Splitting Up Together (2018–…)
- SpongeBob SquarePants (1999–…)
- Sport Billy (1979–1980)
- Spreadsheet (2021–…)
- Spring Tide (2016–…)
- Sprung (2022–…)