Series whose first letter is a digit or another sign
- 3rd Rock from the Sun (1996–2001)
- 4 Blocks (2017–…)
- 4400 (2021–…)
- 45 rpm (2019)
- 49 Days (2011)
- 50M2 (2021–…)
- 5ive Days to Midnight (2004)
- 60 Minutes (1968-…)
- 61st Street (2022–…)
- 666 Park Avenue (2012–2013)
- 68 Whiskey (2020–…)
- 7 Toughest Days (2023-…)
- 72 Cutest Animals (2016–…)
- 72 Dangerous Animals - Asia (2018–…)
- 7Seeds (2019–…)
- 7th Heaven (1996–2007)
- 8 Days (2019–…)
- 8 Out of 10 Cats (2005–…)
- 8 Out of 10 Cats Does Countdown (2012–…)
- 8 Simple Rules (2002–2005)
- 800 Words (2015–2018)
- 9 Ends 2 Out (2007)
- 9-1-1 (2018–…)
- 9-1-1: Lone Star (2020–…)
- 90 Day Fiancé (2014–…)
- 90 Day Fiancé: Before the 90 Days (2017–…)
- 90 Day Fiancé: The Other Way (2019–…)
- 90210 (2008–2013)
- 999: Killer on the Line? (2016–…)
- 9JKL (2017–2018)