Series with the first letter - "S"
- Seven Seconds (2018)
- Seven Worlds, One Planet (2019–…)
- Seventeen Moments of Spring (1973–…)
- Severance (2022–…)
- Sex & Drugs & Rock & Roll (2015–2016)
- Sex and the City (1998–2004)
- Sex Education (2019–…)
- Sex Life (2019–…)
- Sex, Love & Goop (2021–…)
- SF8 (2020–…)
- SGU Stargate Universe (2009–2011)
- Shades of Blue (2016–2018)
- Shades of Guilt (2015–2019)
- Shadowhunters: The Mortal Instruments (2016–…)
- Shaka Zulu (1986)
- Shakespeare & Hathaway: Private Investigators (2018–…)
- Shameless (2011–…)
- Shameless (2004–2013)
- Shark Tank (2009–…)
- Sharp Objects (2018)
- Shaun Micallef's Mad as Hell (2012–2018)
- Shaun the Sheep (2007–2020)
- She (2020–…)
- She diao ying xiong zhuan (2003–…)
- She Is Wow (2013)
- She Was Pretty (2015)
- She-Ra and the Princesses of Power (2018–…)
- She's Gotta Have It (2017–…)
- Shenmue (2022–…)
- Sherlock (2010–…)