Series with titles starting with letter "S"
- Saved by the Bell: The College Years (1993–1994)
- Saving Hope (2012–…)
- Saxondale (2006–2007)
- Scam 1992 the Harshad Mehta Story (2020–…)
- Scandal (2012–2018)
- Scarborough (2019)
- Scarecrow and Mrs. King (1983–1987)
- Scaredy Squirrel (2010–2013)
- Scariest Night of My Life (2017–…)
- Scenes from a Marriage (1973)
- Schitt's Creek (2015–…)
- Schmigadoon! (2021-2023)
- School (1999–…)
- School 2017 (2017)
- School Spirits (2023-…)
- School Tales the Series (2022–…)
- Schooled (2019–…)
- Schulz Saves America (2020–…)
- Sci Fi Science: Physics of the Impossible (2009–…)
- Science and Islam (2009–…)
- Scooby Doo, Where Are You! (1969–1970)
- Scooby-Doo and Guess Who? (2019–…)
- Scooby-Doo and Scrappy-Doo (1979–1983)
- Scooby-Doo! Mystery Incorporated (2010–2013)
- Scooby's Laff-A Lympics (1977–1979)
- Scoop (2023–…)
- Scorpion (2014–2018)
- Scott & Bailey (2011–2016)
- Scott Pilgrim Takes Off (2023)
- Scott the Woz (2017–…)