Series with the first letter - "S"
- Schooled (2019–…)
- Schulz Saves America (2020–…)
- Sci Fi Science: Physics of the Impossible (2009–…)
- Science and Islam (2009–…)
- Scooby Doo, Where Are You! (1969–1970)
- Scooby-Doo and Guess Who? (2019–…)
- Scooby-Doo and Scrappy-Doo (1979–1983)
- Scooby-Doo! Mystery Incorporated (2010–2013)
- Scorpion (2014–2018)
- Scott & Bailey (2011–2016)
- Scott the Woz (2017–…)
- Scream Queens (2015–2016)
- Scream: The TV Series (2015–…)
- Screen One (1985–2002)
- Screen Two (1985–2002)
- Screw (2022–…)
- Scrubs (2001–2010)
- Sea Wolf (2009–…)
- SeaChange (1998–2000)
- SEAL Team (2017–…)
- SeaQuest 2032 (1993–1996)
- Search for the Lost Giants (2014–…)
- Search Party (2016–…)
- Season of Cherry (2014–2015)
- Second Chance (2016)
- Second to Last Love (2016)
- Secret Agent (1964–1967)
- Secret Army (1977–1979)
- Secret City (2016–2018)
- Secret Diary of a Call Girl (2007–2011)