Series with the first letter - "S"
- Sanditon (2019)
- Sandokan (1976)
- Sanford and Son (1972–1977)
- Santa Clarita Diet (2017–…)
- Santa Evita (2022)
- Santo (2022–…)
- Sapphire & Steel (1979–1982)
- SAS Rogue Heroes (2022)
- Satisfaction (2014–2015)
- Saturday Night Live (1975–…)
- Savage Kingdom (2016–2019)
- Savage River (2022–…)
- Save Me (2018–…)
- Save Me (2017–2019)
- Saved by the Bell (1989–1992)
- Saved by the Bell (2020–…)
- Saved by the Bell: The College Years (1993–1994)
- Saving Hope (2012–…)
- Saxondale (2006–2007)
- Scam 1992 the Harshad Mehta Story (2020–…)
- Scandal (2012–2018)
- Scarborough (2019)
- Scarecrow and Mrs. King (1983–1987)
- Scaredy Squirrel (2010–2013)
- Scariest Night of My Life (2017–…)
- Scenes from a Marriage (1973)
- Schitt's Creek (2015–…)
- School (1999–…)
- School 2017 (2017)
- School Tales the Series (2022–…)