Il était une fois... la vie (1987–1988): Season 1, Episode 21 - La guerre des toxines - full transcript

[lively music playing]

♪ Is life, is life, that's life ♪

♪ Sing a song of life ♪

♪ Every heartbeat's a miracle ♪

♪ Feel the rhythm growing ♪

♪ Day by day as we go ♪

♪ Look inside, your body is humming ♪

♪ With a million drums that are drumming ♪

♪ Fill your lungs, get ready ♪

♪ Celebrating the joy
That's life ♪

♪ Is life, is life, that's life ♪



♪ Is life, is life, that's life ♪

WAR ON TOXINS

[Peter] As you know, the human body
has countless enemies:

viruses, bacteria, of various sorts,

sorts which can cause either major illness
or less serious ones,

such as [sneezes] the common cold.

To fight the germs, the body has
a police force of white corpuscles,

which you as cadet lymphocytes
are being trained to become.

There are also the specialists:
the polymorphs,

and of course, the macrophages...

the antibodies, and many, many others.

But the body is also attacked
by a great number of poisons.

Toxins, gases, chemical products,
some of which are natural,

but others, the majority, are manmade.



To protect the body against these toxins,
every cell has special agents

called detoxifying enzymes, which are
produced specifically for this purpose.

[Peter Jr.] We must hurry up, you know,
or we'll be late for lunch again.

[light music playing]

[Jumbo Jr.] Just look at
all that awful pollution.

With all those exhaust fumes
it's a wonder we can even breathe.

[Stroppy coughing]

-[Stroppy] Stop!
-[Foxy shrieks]

-[tires screeching]
-[shouts]

[bright music playing]

[coughing]

[shocked gasps]

[Jumbo Jr.] It looks as if
we've got an invasion.

Here on the tonsil battlefield,
we are in the front line of defense.

Look who are trying to sneak their way in:

our bacterial friends.

[inhales]

[satisfying sounds, chuckling]

Hm? Oh, excuse me, but bacteria
are not the easiest things to digest.

Watch out! There's some more
nasty filth creeping in.

[cop] Don't get so worried, Chief.
They're not germs.

They're only pollution and smoke particles
or something.

But they're unhealthy.

Mm. Well, the enzymes
can take care of them in there.

They're used to dealing
with that type of filth.

[feel-good music playing]

[Hemo] Keep it up, not much further now,
Professor Globus.

Give me your hand. I'll help you.

We've nearly reached
the alveoli of the lung

and then we'll be able to breathe
some lovely pure air.

[gasps]

[joyous cheers and laughter]

[singing]

[groans]

[moans] Hey, how dare you do that? You're
not allowed to throw polluted bubbles.

Oh. Mm?

[Globine] What can this be? It's so dirty,
I'm not going to touch it.

-Yuck! Get away.
-Oh!

[corpuscle]
What kind of contraption is that?

[disgusted exclaim]

[Claire] I am afraid there's still
some pollution down there, Captain.

[Peter Jr.] Right. Well...

Calling all macrophages units.
We have spotted some toxic particles.

Zone 35 of the lung arterioles.

Eliminate at once.

[shouting]

[shouting]

They've gone Captain.
But we'll have to send the macrophages

and other white corpuscles after them.

[Peter Jr.] They'll have difficulty
in finding them.

They're chemical pollutants
and very dangerous.

I don't like the look of them.

[light music playing]

-[enzyme] I have just checked you.
-Hm...

Hm? [muttering]

If I were you I wouldn't have done that.
I would have moved the bishop.

Check again!

Hm... Let's see,
I think I will move my bishop.

Huh? Huh?

Hey, what's that?

-Do you see what's approaching there?
-Hm?

[enzyme 1] It's pollution.
Don't worry about it.

It's outside the cell.

I am sure that the others
will see to it that it's destroyed.

It's your turn.

[enzyme 2]
They look like cell pollutants to me.

They might try to break in,
don’t you think?

Ah no, I assure you,
we are quite safe here.

But some pollutants can penetrate
the membrane.

Uh, I think I will play this one here.
Yes...

[enzyme 1] You only did that
because you're are losing.

[shouts]

[enzyme 3] The toxins are here.
They've broken the cell wall.

-Uh, let's sound the alarm.
-[shouting]

[enzyme 1] Run for your life. [shouting]

[Peter Jr.] We've spotted the enemy.

They're at the cell wall.

Too late. They've entered.

I am afraid they're out of our reach.

[panicked gasping]

Chief, an enemy invasion. Back there.

[chief] What are they then? Regular germs?

Oh no, Chief. They look like pollutants,
uh, toxins, all black and horrible,

and they're approaching the center,
the nucleus.

We must inform
the control center immediately.

Toxins, or so it appears. Uh, all black.

They seem to be heading
for the central control post.

[Maestro] Pinpoint that please,
Chief Enzyme.

-Quickly.
-[gentle music playing]

[Maestro] Ah yes, I recognize them.

Smoke pollutants.
They must be got rid of at all costs.

Oh, dear.

On no account must they be allowed
to reach the nucleus.

If they do, we're in big trouble.

Hey, hey. That's my specialty, Maestro.
I belong to the antibody brigade.

And I'll dismantle
the dirty little monsters in two ticks.

But you're all alone.

-Uh, yes, I am, but not for very long.
-Hm...

You'll have to have a little bit of help.

Those pollutants are tough.

Run along then, while we start instructing
the ribosome factory

-to make reinforcements for you.
-[muttering]

[Maestro] Stop the assembly lines.

Initiate the synthesis for making
the detoxifying enzymes: benzo attackers.

Alert all competent chromosomes
immediately. And hurry up about it.

-This is an emergency.
-Hm-mm.

[light music playing]

Calling chromosome six. Chromosome six
is needed immediately for production of

detoxifying enzymes, urgent.
Chromosome six, please.

I am having a siesta.
Why do they always pick on me?

I really wish they'd leave me alone.

Mm-hm.

[yawns] Very well then,
I can't win with you lot.

I'm coming now.

[light music playing]

A, C, T, G, A, A, T, A.

Ah. The cytochrome genes,
the detoxifying enzymes.

Activate them, would you, please,
immediately?

Ah. Regulatory enzymes,
all of you over here, please.

Cut here
at the start of the antitoxin gene.

-[shrieks]
-[enzyme] Thank you.

And again at the end of the gene
and its message.

Just after the A.

Right, now exit from the cell nucleus
towards the ribosome factory.

-[Maestro] No, no, no. Idiot.
-Huh?

DNA is the information blueprint.

It must never ever leave the cell nucleus,
where it is protected.

Is that quite clear?

A copy, you must make a copy
of that information, remember?

The original must stay where it is,
always. If not, the cell will lose

precious information,
which will never be recovered.

I am sick and tired of having
to repeat this to you. [scoffs]

There's a shortage of iron.

The antitoxin enzymes simply
have to have iron right now.

But why do we need iron in proteins?

[chief] Because the iron
gives them energy.

Go and order some from the spleen;
the great iron reserves,

and quickly, we haven't got time to waste.

Right, Chief, sir. Anything you say.

[muttering]

Hello. Hello.
Am I speaking to the spleen factory?

We need some iron quickly, please.

[voice message] Please telephone later.

Your call cannot be put through
as the lines are blocked.

Please telephone later.
Your call cannot be put through--

Is that the spleen factory?
We need iron. It's urgent.

It's badly needed for the fabrication--

[voice message] This is the pylorus,

the gastro-intestinal
transportation center.

Will you please check the number
you have dialed? This is the pylorus.

Is that the spleen? I have to have
the spleen, the iron reserves.

[operator] This is the spleen.

-What can we do for you, sir?
-Ah!

At last. You've got to help us.
We need iron urgently.

-You simply got to help.
-Hang on.

-What?
-Please calm down, sir.

All you need do is place an order.
Go ahead.

I need two million, uh...

two million three thousand iron atoms
for the fabrication--

I know, sir, for the fabrication

-of detoxifying enzymes.
-Ah!

We have noted your order,
which will be processed immediately.

We thank you for your call.

Well, is the RNA messenger coming or what?

Here it is. Here, Chief.

Good, you're going to have to
cut the message while it's still moving.

And you two: glue the RNA messenger
in place for the detoxifying enzymes.

[light music playing]

Quick, quick! Ligase enzyme, I want you
to stick that lot together immediately.

Ooh...

[grunting]

Come on, you, what's going on?

[groaning]

[pained yell]

Huh?

[groaning]

-[grunts]
-Well, are you coming or not?

[whimpering]

Here. [moans]

Hm...

Mission accomplished with great success.
[silly laugh]

[wicked laugh]

[moans]

Well, what do we have to do?

[Maestro] But you're detoxifying enzymes,
my friends. You're meant to protect

the body against all kinds of toxins.

But I've the impression
that something's missing.

I can't think what on earth it can be.

[bright music playing]

Of course. You need armor.
What's missing is the iron.

[chief] We've placed an urgent order
with the spleen, Maestro.

The iron is en route.

At top speed, Maestro.

-Look, a station.
-[Globus] Yes, it's a marshaling yard.

The spleen's over there.
They must be preparing a delivery,

of iron, no doubt.

[master] Stop!

[whistle blowing]

[driver screams]

[growls] And what's all this about then?

When I allow pedestrians to cross,
they have the right of way.

But this is an urgent delivery of iron.
No way we can't stop now.

[horn blows]

[corpuscle] Oh! Out of the way.

[heavy breathing]

-[Globus] Wait for me.
-[groaning]

-[Hemo] Come on! Up!
-[Globus moans]

-Bye!
-Oh, look at that. They're cheating.

[Globine] Come!

[heavy breathing]

[groans] Oh! It's not fair.
That's just not fair.

-[groans] Here it is!
-[light music playing]

[blacksmith] So you're here at last.
What on earth took you so long then?

It is possible to have delivery problems,
you know.

But here's your iron.
By express, what's more.

[driver] Best quality iron.

[blacksmith] Well, it's not a minute
too soon. I thought you'd never come.

That's what we need.
Go on then, you can go first. Hurry up.

[satisfied exclaims]

Ah, you look great, you know that?

-Really wonderful.
-[Maestro] Have you quite finished?

Huh?

The cell is in great danger
and you have a mission to accomplish.

Off you go.

[light music playing]

[officer] The toxins have entered
on the east side of the cell.

They're in close formation and moving
in the direction of the nucleus.

This is really serious.

The detox enzymes have been commanded
to protect the nucleus at all costs

and to disarm the invaders. Attack!

We're off!

[shouting]

[groaning]

[chief detox] Disperse,
so we can spread the force of attack.

[groans]

Oh, that's it!

Watch out!

Quick, dismantle it. Otherwise,
the poison will never be destroyed.

[shocked gasps] There was one more
of these. Where is it?

[frustrated groan]

This one's mine. Just watch me.

[grunting]

[shouts]

Oh no! It's taken the nucleus.

Warn the chromosomes.
There's danger of mutation.

But I will get him yet!

What on earth is that sound?

[screams] Oh!

Ah...

Oh...

-[cheerful music playing]
-[birds chirping]

[shrieking]

-[assistant] Maestro!
-What was that? Hm? Yes?

Maestro, something terrible has happened.

[Maestro] What's going on?
What's all the noise about?

-Mm...
-[Maestro] A damaged chromosome.

[assistant] It's chromosome four.

[Maestro] There's a danger of mutation,
caused by a chemical pollutant.

-That means that... That...
-Well, a mutation is a change

in the chromosomes
and the changed cell may multiply.

And if that happens,
there's a chance of cancer developing,

The bad cells attack the good ones
and prevent them from working.

But there's no need to panic.
There's still a way out of all this.

-[assistant stutters] But, how, Maestro?
-There are several methods.

Our detoxifying enzymes can keep working,

while our bodyguards
destroy the bad cells.

If they don't,
a serious illness may develop.

The bad cells
haven't started to reproduce.

We must call in our specialist enzymes
to try and repair the DNA.

Activate the repair procedure at once.
It is a matter of extreme urgency!

[beeping]

-Now, we should see some action, I think.
-[bright music playing]

[Endo] Genetic material badly damaged.
That's awful.

[DNA 1] Ah! Stop it.
You're crushing my hand.

[DNA 2] Here. Here, you can use
my shoulder to help you up.

-[Endo] Thanks.
-[DNA 3] My nose. Watch out for my nose.

[Exo] Here. Slowly does it.

All yours, Exo!

[Exo] Well, get to work.

Why aren't you helping us?

Why aren't you helping by keeping quiet?

When you know I am the intellectual type
and need time to think.

I am the one who has to reassemble
the DNA so it fits properly.

Hm-mm.

[yawns]

Can you please pass me
that long piece there?

And you, pass me the red.

Now, this square piece.
Right! Now let's take the whole lot.

-[bright music playing]
-Hm...

A real work of art,
a masterpiece, and now for the repair.

Come along. This way.

And pull and pull and pull...

And pull and pull and pull and pull.

Up there, stand there. Yes, that's good.
Perfect. Now take each other's hand,

and sit down, please. And G,
you take hold of A's hand, please.

Now, keep that still.

Hm... And now you're all right again,
aren't you?

Thank you very much for your help.

Bye-bye.

-Whoa!
-[DNA shrieks]

I have done it.

Repairs carried out with success. Cell
back to normal and good for duplication.

[bright music playing]

DNA's repaired. Everything is okay now.

[cheers]

All that's left
is to put this back inside.

Thank you. Well, there's nothing like
a little rest to recuperate.

Bye!

[Maestro] So, you see,
it's all turned out well.

The human body has a remarkable capacity
to cope with problems.

Let's see what's going on elsewhere.

There, all the toxins have been destroyed.

Very good.
Now, we need the rubbish removers.

Command to all rubbish trucks
on the lysosome route.

Right, stop please,
and clean that mess up.

And these are the lysosomes.
They're called the stomachs of the cell.

[laughs] They digest rubbish
in order to discharge it outside the cell.

[voice] Digestion completed.
Prepare for discharge from the cell.

Digestion completed.
Prepare for discharge from the cell.

Very good, I got that.
Discharge authorized.

[feel-good music playing]

[Hemo] Where does all this dirt come from?

[Globus] All kinds of waste,
which the cell no longer wants

and which may be bad for it.

But don't worry about it.
We're coming to the kidneys

and then we'll be quite clean. Look there.

We're approaching them already.

About time. This is terrible.
I am stained all over.

Just look at me,
I am not even presentable.

The kidneys. They're the center
for cleaning the blood, aren't they?

-Am I right, Professor Globus?
-Indeed they are.

More than a liter of blood
passes through each minute.

[laughing]

Rubbish is purified and thrown out.

-And will we be cleaned?
-[Globus] Yes, you'll see.

Watch out and hold on tight.

-We'll meet up again at the exit.
-Why hold on tight, Professor?

-Is it dangerous?
-Oh no, don't worry about it.

We're entering a glomerulus,
just a simple filtration system.

-We're quite sparkling.
-[Globus] Yes, not a spot of dirt left.

Didn't I tell you that nothing cleans
like the kidneys?

-They remove even the stubbornest stains.
-Tell me, Professor,

where does the reject dirt
eventually go then?

Uhm, well, you see, the body
discharges it all.

So it goes into the bladder
and then what happens?

It just goes into the bladder.

[Hemo] Yes, but then?

Come on, Hemo, you must know that.

I am not quite sure.

[Globus chuckles] You'll see.

[birds chirping]

[lively music playing]